Ann Arbor, Compared to other races, African women are actually more rare breast cancer. But this race is more vulnerable to one of the most malignant type of cancer due to genetic factors.
Cancer type in question is triple negative breast cancer, which in tests give negative results on 3-specific marker. The three markers in question is the estrogen receptor, progesterone receptor and HER-2/neu.
According to a study at the University of Michigan, this type was found in 82 percent of women with breast cancer in Africa. Much higher than in white American woman who is only 16 percent and African-American women 26 percent.
In that study, participants who are involved consisted of 581 African breast cancer patients and 1008 white women at the Henry Ford Health System in Detroit. In addition, researchers also studied 75 female patients in a hospital in Ghana.
If the study had previously said that African women stricken with breast cancer more rare, so this finding is surprising. Because of the diagnosis, when compared with other races, the African origin of breast cancer patients tend to experience it at a younger age and with a more malignant tumor types.
Quoted from ScienceDaily, Friday (07/23/2010), researchers found that most patients were observed in Ghana and triple negative breast cancer. This type is often associated with a genetic disorder that causes mutations in the BRCA1 gene.
"These ancestors of Africa may inherit genes that cause women more susceptible to certain types of cancer. We hope to develop a useful biological marker to assess risk factors for breast cancer triple negative," said Newman, one of penliti involved in the study.
Previously, various research has been widely linked to breast cancer risk with genetic factors. Women of Ashkenazi Jewish ethnicity, for example, including one ethnic inherit a higher risk of breast cancer.
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